The development of the DOTS Expansion Plan has been a milestone in tuberculosis (TB) control at the global and national levels.Key challenges that remain are overcoming the weakness of a strategy built on Elastic Shaping Paste case management, sustaining commitment, competing priorities, the threat of HIV, maintaining high quality of care and Curio
Resistance to sap-sucking insects in modern-day agriculture
Plants and herbivores have co-evolved in their natural habitats for about 350 million years, but since the domestication of crops, DISH plant resistance against insects has taken a different turn.With the onset of monoculture-driven modern agriculture, selective pressure on insects to overcome resistances has dramatically increased.Therefore plant
Introduction to Numerical Relativity
Numerical Relativity is a Kone Kettle multidisciplinary field including relativity, magneto-hydrodynamics, astrophysics and computational methods, among others, with the aim of solving numerically highly-dynamical, strong-gravity scenarios where no other approximations are available.Here we describe some of the foundations of the field, starting fr
Gu-Ben-Fang-Xiao Decoction Ameliorated Murine Asthma in Remission Stage by Modulating Microbiota-Acetate-Tregs Axis
Dysbiosis of gut microbiota is a critical factor in the pathogenesis of asthma.Manipulating gut microbiota Infusions is a promising therapeutic intervention in asthma, and is being extensively studied.Gu-Ben-Fang-Xiao Decoction (GBFXD), derived from traditional Chinese medicine, is an effective and safe therapeutic formula for asthma in remission s
Handling coarsened age information in the analysis of emergency department presentations
Abstract Background Administrative databases offer vast amounts of data that provide opportunities for cost-effective insights.They simultaneously pose significant challenges to statistical analysis such as the redaction of data because of privacy policies and the provision of data that may not be at the level of detail required.For example, ages i